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Funded Project Details - FY2021




Project Number:

I01BX003265-01A1
Title: MIF-mediated Mechanisms in Emphysema
Principal Investigator:

Patty J. Lee

Location: Durham, NC
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: January 2017 - September 2021
FY 2021 Funding Amount: $165,825
Total Award Amount
(all years):
$680,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Chronic Obstructive Pulmonary Disease (COPD) has reached epidemic proportions but specific therapies do not exist. Emphysema is a major subset of COPD and is defined histopathologically as enlarged airspaces, which result in ineffective gas exchange. Aside from age, cigarette smoke (CS) exposure is one of the most common identifiable risk factors for COPD. Understanding mechanisms of CS-induced emphysema will allow us to develop effective therapies for a potentially modifiable lung disease that...



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