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Funded Project Details - FY2021

Project Number:

Title: The Role of Endothelial Dysfunction in Arteriovenous Fistula Maturation
Principal Investigator:

Timmy Lee

Location: Birmingham, AL
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: October 2016 - March 2021
FY 2021 Funding Amount: $30,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


    Project Summary/Abstract The vascular access is the “Achilles Heel” of the hemodialysis procedure. Sixty percent of arteriovenous fistulas (AVF) that are created fail to mature successfully for dialysis use (AVF non-maturation), resulting in a very significant clinical morbidity and mortality for hemodialysis patients. On a radiologic level, AVF non- maturation is most commonly characterized by a juxta-anastomotic stenosis, and at a histological level it is characterized by a combination of...

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