Office of Research & Development |
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Project Number: | I01BX003387-01A1 |
Title: | The Role of Endothelial Dysfunction in Arteriovenous Fistula Maturation |
Principal Investigator: | Timmy Lee |
Location: | Birmingham, AL |
Congressional District Code: | 7 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | October 2016 - March 2021 |
FY 2021 Funding Amount: | $30,000 |
Total Award Amount (all years): |
$783,654 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary/Abstract The vascular access is the “Achilles Heel” of the hemodialysis procedure. Sixty percent of arteriovenous fistulas (AVF) that are created fail to mature successfully for dialysis use (AVF non-maturation), resulting in a very significant clinical morbidity and mortality for hemodialysis patients. On a radiologic level, AVF non- maturation is most commonly characterized by a juxta-anastomotic stenosis, and at a histological level it is characterized by a combination of... |