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Project Number: | I01BX002750-06A1 |
| Title: | Regulation of Innate Immunity and Inflammation Through Nuclear Reprogramming |
| Principal Investigator: | Jack J Hawiger |
| Location: | Nashville, TN |
| Congressional District Code: | 5 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2020 - September 2024 |
| FY 2021 Funding Amount: | $226,700 |
| Total Award Amount (all years): |
$729,900 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: PROJECT SUMMARY Regulation of Innate Immunity and Inflammation Through Nuclear Reprogramming We propose to advance our mechanistic studies of innate immunity and inflammation in severe infections that evolve into their end stage, septic shock, thereby threatening the lives of wounded soldiers on the battlefield, our Veterans, and the civilian population. Those Veterans (and non-Veteran patients) between the ages of 65 to 85 are particularly prone to septic shock with a 45% mortality rate while m... |