Office of Research & Development

Technologies with Multiple Patents

Please Note: The technologies listed below are not available to the public at this time. These technologies are in the early stages of research and require further development before they are ready for the marketplace. The VA is currently in the process of identifying potential companies who may be interested in licensing and/or further developing the technology through Cooperative Research and Development Agreements (CRADA). Through cooperative research initiatives such as these, it is our hope and goal that commercial products will be fully developed and made available to benefit veterans and others.


Below is a list of technologies have more than one patents.

View By: Complete List | Topic | Fiscal Year

Date Posted

Reference No.

Patent No.

Title

Topic

05/07/2003

00-025

6,569,615

Composition and methods for tissue preservation

Diagnostic

07/19/2011

00-025

7,981,596

Tissue preservation with a salt solution isotonic with interstitial fluids

Medical Device

11/22/2016

00-074

7,189,396

Delivery system using MAB 3E10 and mutants and/or functional fragments thereof

Therapeutic - Immunology/Autoimmune

11/29/2016

00-074

9,505,809

Proteins with repetitive bacterial-IG-like (BIG) domains present in Leptospira species

Genomics

07/18/2007

00-075

9,707,207

Method for diagnosing, preventing, and treating neurological diseases

Neurology

10/27/2015

00-075

9,168,275

Method of Treating Autism and Therapies for Gastrointestinal and Neurological Disorders

Therapeutic - GI

09/23/2003

00-137

6,623,022

Folding commode and shower wheelchair

Rehab/Assistive Device

08/12/2003

00-137

6,604,750

Commode and shower wheelchair

Rehab/Assistive Device

12/06/2016

02-029

9,513,289

Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide

Genomics

12/06/2016

02-029

9,513,288

Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide phosphodiesterases

Genomics

05/13/2014

02-029

8,722,866

Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide phosphodiesterases

Genomics

04/08/2008

02-035

7,354,897

Method and composition for inhibiting or slowing blood coagulation

Therapeutic - General

08/10/2010

02-035

7,771,956

Method for detecting the presence of a phospholipid

Diagnostic

05/30/2003

03-044

7,361,474

Diagnosis and Monitoring of Prostate Cancer Patients by Measurement of Serum Macrophage Migration Inhibitory Factor.

Diagnostic

06/29/2010

03-044

7,745,121

Polymorphism in the macrophage migration inhibitory factor (MIF) gene as marker for prostate cancer

Therapeutic - Oncology

05/15/2015

03-107

9,133,250

Proteins with repetitive Bacterial-Ig-like (BIG) domains present in Leptospira species

Genomics

08/12/2014

03-107

8,802,835

Proteins with repetitive bacterial-Ig-like (Big) domains present in leptospira species

Genomics

09/20/2011

03-107

8,021,673

Proteins with repetitive Bacterial-Ig-like (Big) domains present in Leptospira species

Genomics

05/03/2011

03-107

7,935,357

Proteins with repetitive Bacterial-Ig-like (Big) domains present in Leptospira species

Genomics

11/01/2016

03-135

9,480,418

Systems and methods for the screening and monitoring of inner ear function

Diagnostic

05/17/2016

03-135

9,339,216

Systems and methods for the screening and monitoring of inner ear function

Diagnostic

07/14/2015

03-150

9,079,936

Derivatives of APF and methods of use

Diagnostic

07/21/2015

03-150

9,085,604

Antiproliferative factor and methods of use

Therapeutic - Oncology

03/25/2015

03-150

8,680,056

Antiproliferative factor and methods of use

Therapeutic - Oncology

01/27/2015

03-166

8,940,535

Stem cell culture medium and method of using said medium and the cells

Genomics

12/06/2016

03-166

9,513,288

Stem cell culture medium and method of using said medium and the cells

Genomics

03/10/2015

03-169

8,975,231

Bone morphogenic protein binding peptide

Genomics

05/10/2016

03-169

9,333,237

Bone morphogenic protein binding peptide

Genomics

06/24/2014

03-169

8,759,296

Bone morphogenic protein binding peptide

Genomics

01/26/2016

04-003

9,243,051

Monomeric recombinant MHC molecules useful for manipulation of antigen-specific T-cells

Genomics

02/19/2013

04-003

8,377,447

Monomeric recombinant MHC molecules useful for manipulation of antigen-specific T cells

Genomics

11/27/2012

04-079

8,317,700

Methods and devices for non-invasive analyte measurement

Diagnostic

11/27/2012

04-079

8,318,680

Method and peptide for regulating cellular activity

Genomics

07/07/2009

04-079

7,557,086

Compositions and methods for the evaluation and resuscitation of cadaveric hearts for transplant

Therapeutic - Pain/Inflammation/Arthritis

12/14/2010

04-114

7,851,169

Compositions and methods for inhibiting squamous cell carcinoma

Therapeutic - Oncology

01/25/2011

04-114

7,875,277

Compositions and methods for inhibiting squamous cell carcinoma

Therapeutic - Oncology

01/05/2016

04-129

9,226,904

Pharmacological treatment of Parkinson's disease

Neurology

06/30/2015

04-129

9,066,903

Pharmacological treatment of Parkinson's disease

Neurology

10/19/2010

04-196

7,816,140

Composition and methods for osteogenic gene therapy

Genomics

10/17/2017

04-196

9,789,162

Systemic and local ex vivo gene therapy of the skeleton

Genomics

07/08/2014

04-196

8,772,571

Compositions and methods for osteogenic gene therapy

Genomics

10/04/2016

04-196

9,458,215

Compositions and methods for osteogenic gene therapy

Genomics

10/28/2014

06-025

8,870,786

Method and apparatus for tinnitus evaluation

Rehab/Assistive Device

01/15/2013

06-025

8,353,846

Method and apparatus for tinnitus evaluation

Rehab/Assistive Device

11/12/2013

06-028

8,580,769

Treatment of obesity, metabolic syndrome, and diabetes with protein kinase C inhibitors

Therapeutic - Endocrine

11/05/2013

06-028

8,574,640

Combined effects of nutrients on proliferation of stem cells

Other - Null

08/15/2015

06-032

9,114,133

Methods for treating neural cell swelling

Neurology

07/10/2006

06-032

Tetrahydrobiopterin Improves Cardiac Diastolic Relaxation: A New Therapy for Diastolic Dysfunction

Therapeutic - Cardiology/Respiratory

05/26/2015

06-070

9,040,233

Methods for detecting a Mycobacterium tuberculosis infection

Diagnostic

08/01/2017

06-070

9,717,782

Methods for producing an immune response to tuberculosis

Therapeutic - Immunology/Autoimmune

01/29/2013

06-070

8,361,707

Methods for detecting a Mycobacterium tuberculosis infection

Diagnostic

11/26/2013

06-148

8,592,447

Acridone compounds

Mental Health

05/24/2015

06-148

8,987,296

Acridone compounds

Mental Health

04/06/2010

07-025

7,690,057

Folding Frame Motorized Prone Cart

Rehab/Assistive Device

12/29/2009

07-025

D606,910

Prone cart

Rehab/Assistive Device

08/23/2011

07-111

8,003,324

Modulation of sodium channels by nicotinamide adenine dinucleotide

Therapeutic - Cardiology/Respiratory

08/25/2015

07-111

9,114,151

Method for modulating or controlling sodium channel current by reactive oxygen species (ROS) originating from mitochondria

Therapeutic - Cardiology/Respiratory

12/29/2015

07-111

9,220,720

Method for ameliorating or preventing arrhythmic risk associated with cardiomyopathy

Therapeutic - Cardiology/Respiratory

12/15/2015

07-111

9,211,301

Method for ameliorating or preventing arrhythmic risk associated with cardiomyopathy by improving conduction velocity

Therapeutic - Cardiology/Respiratory

08/25/2015

07-111

9,114,133

Method of improving diastolic dysfunction

Therapeutic - Cardiology/Respiratory

06/09/2015

07-111

9,050,350

Method for modulating or controlling connexin 43(Cx43) level of a cell and reducing arrhythmic risk

Therapeutic - Cardiology/Respiratory

07/09/2013

08-003

8,481,283

Pressure Assisted Molecular Recovery (PAMR) and Pressure Assisted Antigen Retrieval (PAAR)

Diagnostic

10/16/2012

08-003

8,288,122

Pressure-assisted molecular recovery (PAMR) of biomolecules, pressure-assisted antigen retrieval (PAAR), and pressure-assisted tissue histology (PATH)

Diagnostic

05/06/2014

08-016

8,716,266

Use of PKC-iota inhibitors for the treatment of glioma

Therapeutic - Oncology

12/10/2013

08-016

8,603,758

Prostate carcinogenesis predictor

Therapeutic - Oncology

07/14/2015

08-016

9,078,915

Prostate carcinogenesis predictor

Therapeutic - Oncology

04/04/2017

08-025

9,610,320

Surgical applications for BMP binding protein

Therapeutic - General

04/04/2017

08-025

9,611,301

GB virus C (hepatitis G virus) E2 glycoprotein as an immunomodulatory agent

Therapeutic - Immunology/Autoimmune

10/15/2013

08-027

8,557,867

Inhibitors of NC.sub.CA-ATP channels for therapy

Neurology

06/28/2016

08-027

9,375,438

Inhibitors of NC.sub.CA-ATP channels for therapy

Neurology

02/03/2015

08-029

8,945,823

Compositions and methods for tissue preservation

Diagnostic

10/22/2013

08-029

8,563,233

Blood substitute solution

Medical Device

06/07/2016

08-068

9,358,226

Triarylmethane analogs and their use in treating cancers

Therapeutic - Oncology

05/07/2013

08-068

8,435,979

Use of imipramine blue and analogs thereof in treating cancers

Therapeutic - Oncology

09/23/2014

08-068

8,841,276

Fulvene and fulvalene analogs and their use in treating cancers

Therapeutic - Oncology

01/01/2013

08-073

8,344,060

Dynamic mechanical polyner nancomposites

Other - Null

02/16/2016

08-073

9,260,573

Dynamic mechanical polyner nancomposites

Other - Null

07/12/2016

09-017

9,387,082

Hydrogel arthroplasty device

Medical Device

03/25/2014

09-017

8,679,190

Hydrogel arthroplasty device

Medical Device

04/05/2014

09-020

8,691,942

N- and C- terminal substituted antagonistic analogs of GH-RH

Genomics

02/16/2016

09-020

9,260,504

N- and C- terminal substituted antagonistic analogs of GH-RH

Genomics

11/03/2015

09-070

9,173,930

Methods for detecting a Mycobacterium tuberculosis infection

Diagnostic

02/25/2014

09-070

8,658,350

Methods for detecting a Mycobacterium tuberculosis infection

Diagnostic

11/29/2016

09-070

9,506,922

Methods for detecting a mycobacterium tuberculosis infection

Diagnostic

11/30/2010

09-070

7,842,299

Methods for producing an immune response to tuberculosis

Therapeutic - Immunology/Autoimmune

07/07/2015

09-137

9,072,709

Enhancement of bone morphogenic protein (BMP) retention with BMP binding peptide (BBP)

Genomics

04/09/2013

09-137

8,415,302

Surgical applications for BMP binding protein

Genomics

03/15/2016

10-021

9,283,272

Targeting intracellular target-binding determinants with intracellular antibodies

Genomics

10/13/2015

10-021

9,155,801

Amino acid sequences which enhance peptide conjugate solubility

Therapeutic - Immunology/Autoimmune

01/24/2017

10-062

9,549,684

System and method for reconstructing cardiac signals associated with a complex

Therapeutic - Cardiology/Respiratory

09/16/2014

10-062

8,838,223

Method for analysis of complex rhythm disorders

Therapeutic - Cardiology/Respiratory

01/26/2016

10-062

9,241,667

System and method for reconstructing cardiac signals associated with a complex rhythm disorder

Therapeutic - Cardiology/Respiratory

07/28/2015

10-062

9,089,269

System and method for reconstructing cardiac signals associated with a complex

Therapeutic - Cardiology/Respiratory

08/01/2017

10-062

9,717,436

System and method for reconstructing cardiac signals associated with a complex rhythm disorder

Therapeutic - Cardiology/Respiratory

09/16/2014

10-062

8,838,222

Method for treating complex rhythm disorders

Therapeutic - Cardiology/Respiratory

10/21/2014

10-062

8,868,169

Method and system for detection of biological rhythm disorders

Therapeutic - Cardiology/Respiratory

09/13/2016

10-063

9,439,573

Method for analysis of complex rhythm disorders

Therapeutic - Cardiology/Respiratory

07/19/2016

10-063

9,393,425

Methods and systems for detecting and treating heart instability; Method for analysis of complex rhythm disorders;System for analysis of complex rhythm disorders

Therapeutic - Cardiology/Respiratory

03/21/2017

10-086

9,597,372

Vault complexes for cytokine delivery

Therapeutic - Oncology

12/30/2014

10-086

8,920,807

Vault complexes for cytokine delivery

Genomics

09/15/2015

10-132

9,133,460

Methods for determining and inhibiting rheumatoid arthritis associated with the BRAF oncogene in a subject

Therapeutic - Pain/Inflammation/Arthritis

03/24/2014

10-132

8,680,066

Methods for determining and inhibiting rheumatoid arthritis associated with the BRAF oncogene in a subject

Therapeutic - Pain/Inflammation/Arthritis

11/25/2014

10-161

8,895,018

Recombinant T-cell receptor ligand for the treatment of cognitive and neuropsychiatric impairment induced by substance addiction

Mental Health

04/01/2014

10-161

8,685,404

Recombinant T-cell receptor ligand for the treatment of cognitive and neuropsychiatric impairment induced by substance addiction

Mental Health

12/30/2014

11-057

8,920,789

Use of polymer D-lactic acid (PDLA) or equivalents thereof to inhibit growth of cancer cells and diagnose cancers

Therapeutic - Oncology

07/05/2016

11-057

9,382,376

Use of polymer D-lactic acid (PDLA) or equivalents thereof to inhibit growth of cancer cells and diagnose cancers

Therapeutic - Oncology

01/04/2012

11-099

Apparatus for Heat Enhanced Pulse Oximetry Measurements

Medical Device

10/24/2017

11-099

9,795,332

Method and pulse oximeter apparatus using chemical heating

Diagnostic

04/05/2016

11-134

9,301,688

Systems for screening the skin condition of the plantar surface of the feet

Diagnostic

10/17/2017

11-134

9,788,792

System for screening skin condition for tissue damage

Personalized Medicine

12/16/2014

11-147

8,911,958

Methods for assessing modified LDL immune complexes in subjects having or at risk of coronary artery disease

Therapeutic - Cardiology/Respiratory

10/29/2013

11-147

8,568,995

Methods for assessing modified LDL immune complexes in subjects having or at risk of coronary artery disease

Therapeutic - Cardiology/Respiratory

08/02/2016

12-007

9,403,895

Production and delivery of a stable collagen

Therapeutic - Immunology/Autoimmune

05/26/2015

12-007

9,040,484

Production and delivery of a stable collagen

Therapeutic - Immunology/Autoimmune

12/06/2016

12-039

9,511,086

Method for improving immune system function by administering agents that

Genomics

04/01/2014

12-039

8,685,938

Methods to enhance T-cell mediated immune response

Therapeutic - Immunology/Autoimmune

08/05/2014

12-048

8,796,233

Methods and systems for modulating hormones and related methods, agents and compositions08/0

Therapeutic - GI

03/01/2016

12-048

9,272,051

Methods and systems for modulating hormones and related methods, agents and compositions

Therapeutic - GI

06/06/2017

12-273

9,668,666

System and method for reconstructing cardiac activation information

Therapeutic - Cardiology/Respiratory

06/16/2015

12-273

9,055,877

System and method for reconstructing cardiac activation information

Therapeutic - Cardiology/Respiratory

12/29/2015

12-273

9,220,427

System and method for reconstructing cardiac activation information

Therapeutic - Cardiology/Respiratory

06/16/2015

12-273

9,055,876

System and method for reconstructing cardiac activation information

Therapeutic - Cardiology/Respiratory

10/18/2016

12-273

9,468,387

System and method for reconstructing cardiac activation information

Therapeutic - Cardiology/Respiratory

05/23/2017

12-274

9,655,535

System and method for targeting heart rhythm disorders using shaped ablation

Therapeutic - Cardiology/Respiratory

03/15/2016

12-274

9,282,910

System and method for targeting heart rhythm disorders using shaped ablation

Therapeutic - Cardiology/Respiratory

07/19/2016

12-275

9,392,948

System and method of identifying sources for biological rhythms

Diagnostic

08/09/2016

12-275

9,408,536

System and method of identifying sources for biological rhythms

Diagnostic

08/08/2017

12-275

9,724,009

System and method of identifying sources for biological rhythms

Therapeutic - Cardiology/Respiratory

05/26/2015

12-292

9,042,992

Protecting airways

Therapeutic - Cardiology/Respiratory

06/29/2016

12-292

9,375,568

Controlling coughing and swallowing

Medical Device

06/02/2015

12-314

9,044,369

Mobile manual standing wheelchair

Rehab/Assistive Device

12/09/2014

12-314

8,905,421

Manual wheelchair system for improved propulsion and transfers

Rehab/Assistive Device

09/20/2016

12-314

9,445,958

Manual wheelchair system for improved propulsion and transfers

Rehab/Assistive Device

10/24/2017

12-314

9,795,522

Collapsible manual wheelchair system for improved propulsion and transfers

Rehab/Assistive Device

03/28/2017

2016-079

9,604,056

Methods and systems for treating neurological movement disorders

Neurology

03/29/2016

2016-079

9,295,838

Methods and systems for treating neurological movement disorders

Neurology

03/17/2015

32-149

8,980,952

Methods for treating brain swelling with a compound that blocks a non-selective cation channel

Neurology

08/18/2015

32-149

9,107,600

System and method for reconstructing cardiac activation information

Therapeutic - Cardiology/Respiratory

06/29/2010

99-017

7,745,691

Genetically modified mouse lacking diacylglycerol acyltransferase-1 (DGAT-1) activity

Therapeutic - Endocrine

06/29/2010

99-017

7,745,691

Genetically modified mouse lacking diacylglycerol acyltransferase-1 (DGAT-1) activity

Therapeutic - Endocrine


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