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Funded Project Details - FY2021

Project Number:

Title: Circadian rhythms and cell survival in lithium responsive bipolar disorder.
Principal Investigator:

Michael J McCarthy

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: April 2017 - March 2021
FY 2021 Funding Amount: $82,500
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Bipolar disorder (BD) is a common mental illness that affects 1‐2% of the world's population, including >100,000  veterans, causing severe mood symptoms, volumetric of loss of brain gray matter, and elevated rates of suicide. Among  its symptoms, BD is associated with disrupted daily 24 hr rhythms (circadian rhythms) in sleep and activity. However,  due to similarities and overlap with other psychiatric syndromes, it is commonly misdiagnosed and treatment delays are  frequent. Lithium is an exce...

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