Phosphate Lowering to Treat Vascular Dysfunction in Chronic Kidney Disease
Congressional District Code:
Clinical Science R&D
July 2014 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Chronic kidney disease (CKD) is a major health concern both in the general and Veteran populations. Indeed,the prevalence of CKD in a large Veteran population is 20%. Cardiovascular disease (CVD) is significantlyincreased in CKD and is an important cause of morbidity and mortality. As much as 80% of all CVD isassociated with vascular dysfunction, particularly impaired endothelium-dependent dilation (EDD), measuredby brachial artery flow-mediated dilation (FMDBA), and stiffening of the large elas...