VA Central IRB Submissions

The VA Central IRB uses IRBNet to support management, submission and review of research protocols. All research submissions must be submitted through IRBNet. 

If you are new to IRBNet, please register for a user account at gov.irbnet.org. Registration instructions can be found here. Additional training resources are also available on the VAIRRS SharePoint portal. (VA network access only). For questions please contact your local research office for guidance. 

What forms do I need to submit and where can I find them?

Instructions for the VA Central IRB application process and all VA Central IRB forms are available in IRBNet under Forms and Templates. 

Submitting a multi-site project to the VA Central IRB is a two-part process. The first part pertains to the submission of the protocol and supporting documents by the Principal Investigator (PI). In addition, the PI submits all waiver requests as they apply to the study, as well as model informed consent documents, HIPAA authorizations, and recruitment materials as applicable. The second part involves the submission of Local Site Investigator (LSI) Applications after the PI application has been approved.

A simplified flowchart and detailed instructions guiding the entire VA Central IRB application and review process for PI and LSI New Project submissions can be found on the in IRBNet under Forms and Templates.

If you have question or when filling out any of the forms, you may contact the VA Central IRB general e-mail address at vacentralirb@va.gov. If able, include the name of your study, funding source, Investigator's name, and number of VA sites that will be participating in the study. One of our VA Central IRB staff will get back to you to answer your questions. 

Questions about VA Research or the website? Email VA Research