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Funded Project Details - FY2021




Project Number:

IK2RX001476-01A1
Title: Tissue-Engineered Constructs for Treatment of Intervertebral Disc Degeneration
Principal Investigator:

Harvey Smith

Location: Philadelphia, PA
Congressional District Code: 2
Research Service: Rehabilitation R&D
Project Period: October 2014 - March 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$1,658,386
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

DESCRIPTION The objective of this project is to develop a tissue-engineered construct including an engineered nucleus pulposus and annulus fibrosus to treat defects of the annulus fibrosus (AF) and degenerative changes of the intervertebral disc (IVD). Three Specific Aims are pursued: " Specific Aim 1 will consist of establishing in vitro tissue engineered NP fabrication from rabbit and human NP and MSC cells in hyaluronic acid (HA)-based hydrogel constructs, and evaluation of cell via...



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