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Funded Project Details - FY2021




Project Number:

I01CX001183-01A1
Title: Systemic sclerosis (SSc) vasculopathy: Improved clinical monitoring and treatment
Principal Investigator:

Tracy M Frech

Location: Salt Lake City, UT
Congressional District Code: 2
Research Service: Clinical Science R&D
Project Period: January 2016 - December 2020
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$649,538
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Systemic sclerosis (SSc; scleroderma) is a multi-organ systemic disease characterized by activation of immune cells, which results in vascular dysfunction (vasculopathy) and subsequent scarring (fibrosis). SSc has a higher than expect prevalence in the US military. Although SSc is heterogeneous in the extent of organ involvement and prognosis, it is accepted that all SSc cases have a progressive and usually devastating course. Since vasculopathy precedes fibrosis in this disease, a focus on unde...



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