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Project Number: | I01CX001183-01A1 |
| Title: | Systemic sclerosis (SSc) vasculopathy: Improved clinical monitoring and treatment |
| Principal Investigator: | Tracy M Frech |
| Location: | Salt Lake City, UT |
| Congressional District Code: | 2 |
| Research Service: | Clinical Science R&D |
| Project Period: | January 2016 - December 2020 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$649,538 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Systemic sclerosis (SSc; scleroderma) is a multi-organ systemic disease characterized by activation of immune cells, which results in vascular dysfunction (vasculopathy) and subsequent scarring (fibrosis). SSc has a higher than expect prevalence in the US military. Although SSc is heterogeneous in the extent of organ involvement and prognosis, it is accepted that all SSc cases have a progressive and usually devastating course. Since vasculopathy precedes fibrosis in this disease, a focus on unde... |