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Funded Project Details - FY2021

Project Number:

Title: Cholesterol regulation of Macrophage Inflammation and Vascular Diseases
Principal Investigator:

Shobha Ghosh

Location: Richmond, VA
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: January 2016 - December 2020
FY 2021 Funding Amount: $25,302
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Low grade chronic inflammation associated with obesity is the underlying cause of the development of metabolic diseases including Type 2 diabetes (T2DM) and atherosclerosis. The most important characteristics of chronic inflammation are its persistence and inability to resolve resulting in lack of restoration of homeostasis and development of metabolic diseases. In contrast to classical inflammation which is triggered by an injury or infection, this low grade chronic inflammation is “sterile” in...

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