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Funded Project Details - FY2021




Project Number:

I01BX001164-05
Title: CARP-1: A Potential Therapeutic Agent for Breast Cancer
Principal Investigator:

Arun Rishi

Location: Allen Park, MI
Congressional District Code: 13
Research Service: Biomedical Laboratory R&D
Project Period: January 2016 - December 2020
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$999,968
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Despite recent advances in clinical management, the molecular complexity of triple-negative breast cancers (TNBC) and therapy-associated side effects often limit effectiveness of many therapies. Development of new and improved strategies for TNBC treatment remains urgent. We previously discovered an apoptosis regulatory protein CARP-1/CCAR1. CARP-1 functions to transduce cell growth as well as chemotherapy (adriamycin, etoposide, or Iressa)-dependent inhibitory signaling. CARP-1 expression corre...



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