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Funded Project Details - FY2021

Project Number:

Title: Maximizing Spike - Timing Dependent Plasticity after Spinal Cord Injury
Principal Investigator:

Martin Oudega

Location: Hines, IL
Congressional District Code: 14
Research Service: Rehabilitation R&D
Project Period: April 2016 - March 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


 DESCRIPTION (provided by applicant): Abstract: Our overall goal is to develop new clinical approaches to restore upper-limb function after incomplete cervical spinal cord injury (SCI). Corticospinal tract (CST) axons are involved in controlling upper-limb function. Paired-pulse induced spike-timing dependent plasticity (STDP) enhances synaptic strength between residual CST axons and spinal motoneurons (SMNs) resulting in temporary improvements in upper-limb function in humans with inco...

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