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Funded Project Details - FY2021




Project Number:

I01RX001613-01A2
Title: GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures
Principal Investigator:

Chandramohan Wakade

Location: Augusta, GA
Congressional District Code: 10
Research Service: Rehabilitation R&D
Project Period: November 2015 - March 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$1,035,103
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

 DESCRIPTION (provided by applicant): Project Summary/Abstract We are excited to observe significant differences in the GPR109A levels in the white blood cells (macrophages) of Parkinson's disease (PD) patients and control individuals. Moreover, we observed similar changes in the GPR109A expressions in the substantia nigra regions that co-localize with the microglia of the PD patients and age-matched controls. We are the first lab to denote these changes. GPR109A is an anti- inflammatory...



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