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Funded Project Details - FY2021

Project Number:

Title: KCNQ Channels in Airway Smooth Muscle Physiology and Disease
Principal Investigator:

Kenneth L Byron

Location: Hines, IL
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: January 2016 - December 2020
FY 2021 Funding Amount: $27,130
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


 DESCRIPTION (provided by applicant) Asthma is a chronic respiratory disease characterized by reversible airway obstruction and hyper- responsiveness of the airways to bronchoconstrictor stimuli. Veterans represent a large cohort of asthma sufferers, many of whom do not achieve relief of symptoms with available therapies. Reversible airway obstruction in asthma results primarily from hypercontraction of airway smooth muscle cells (ASMCs) in the bronchioles of the lung. The mechanisms...

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