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Funded Project Details - FY2021




Project Number:

I01BX002914-01A1
Title: Inhibition of the Fas/FasL system in experimental acute lung injury
Principal Investigator:

Gustavo Matute-Bello

Location: Seattle, WA
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: January 2016 - December 2020
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$941,319
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

 DESCRIPTION (provided by applicant) The acute respiratory distress syndrome (ARDS) is an important clinical problem in the United States, affecting 200,000 patients per year and resulting in death of approximately 75,000 persons. Our laboratory is interested in the role of the Fas/FasL system in the pathophysiology of acute lung injury (ALI) in humans and animal models. This system is comprised of the membrane surface receptor Fas (CD95) and its cognate ligand, FasL (CD178). Binding...



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