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Project Number: | I01BX002695-01A2 |
| Title: | Peripheral and Central Pain Generators of Chronic Trigeminal Neuropathic Pain |
| Principal Investigator: | Karin W High |
| Location: | Albuquerque, NM |
| Congressional District Code: | 6 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2016 - December 2021 |
| FY 2021 Funding Amount: | $127,250 |
| Total Award Amount (all years): |
$1,149,621 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant): ABSTRACT Persisting dysfunctional neuroplasticity in peripheral nerves as well as in the brain exert powerful influences on the pain experience. For example, facial trauma suffered by military personnel may heal, yet months later progress to a chronic neuropathic pain state. A facial laceration trigeminal nerve trauma model (CCI-ION) is utilized in our pursuit of mechanistic support for repurposing a noradrenergic (NA) therapeutic currently in u... |