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Funded Project Details - FY2021

Project Number:

Title: Peripheral and Central Pain Generators of Chronic Trigeminal Neuropathic Pain
Principal Investigator:

Karin W High

Location: Albuquerque, NM
Congressional District Code: 6
Research Service: Biomedical Laboratory R&D
Project Period: January 2016 - December 2021
FY 2021 Funding Amount: $127,250
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


 DESCRIPTION (provided by applicant): ABSTRACT Persisting dysfunctional neuroplasticity in peripheral nerves as well as in the brain exert powerful influences on the pain experience. For example, facial trauma suffered by military personnel may heal, yet months later progress to a chronic neuropathic pain state. A facial laceration trigeminal nerve trauma model (CCI-ION) is utilized in our pursuit of mechanistic support for repurposing a noradrenergic (NA) therapeutic currently in u...

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