Gastrointestinal Colonization of Diarrheagenic Clostridium difficile
Congressional District Code:
Biomedical Laboratory R&D
October 2015 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
DESCRIPTION (provided by applicant): The overall goal of this proposal is to significantly expand on findings from our ongoing Merit award-supported work to further interrogate gastrointestinal tract colonization and disease establishment of the diarrheagenic pathogen Clostridium difficile. To enable this project, we have identified unique bacterial factors that mediate C. difficile interaction(s) with the host intestine. Three Specific Aims are proposed. First, we will expand on our...