Funded Project Details - FY2021
|Title:|| Neuronal Subtype Specific Epigenetic Regulation in Schizophrenia|
Stella Plevan (Dracheva)
|Congressional District Code:
||Biomedical Laboratory R&D
|| April 2016 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
DESCRIPTION (provided by applicant): Several candidate risk genes and genomic regions for schizophrenia (SZ) have been identified as well as numerous environmental risk factors. The etiology of SZ, however, remains unknown. Some of the environmental influences may act through epigenetic mechanisms (e.g., DNA methylation and histone modifications) which can alter gene expression by influencing functional DNA elements (e.g., promoters or enhancers), thus altering transcription. Accumul...
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