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Project Number: | I01BX002839-01A2 |
| Title: | Regulation of Matrix Metallopeptidase 9 by Apolipoprotein E |
| Principal Investigator: | Corbin Bachmeier |
| Location: | Bay Pines, FL |
| Congressional District Code: | 13 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2016 - June 2021 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$962,948 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a neurodegenerative process characterized by the deposition of beta- amyloid proteins (Aβ) in the brain and cerebrovasculature. While AD has always been a concern for our aging Veterans, the propensity for head injuries sustained in combat has placed our Veterans at even greater risk for developing AD than the general population. Mounting evidence now suggests the excessive accumulation of Aβ in AD is the result of impa... |