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Funded Project Details - FY2021




Project Number:

I01RX001964-01A1
Title: Reducing Brain Hyperglycolysis: A Novel Strategy for Hyperglycemia after Stroke
Principal Investigator:

Yuchuan Ding

Location: Allen Park, MI
Congressional District Code: 13
Research Service: Rehabilitation R&D
Project Period: March 2016 - February 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$1,077,472
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

 DESCRIPTION: Hyperglycemia (i.e., elevated blood glucose) affects approximately 40% of acute ischemic stroke patients, regardless of a diabetes history. In experimental and clinical studies, hyperglycemia exacerbates ischemic brain injury by perpetuating aberrant glucose metabolism and hyperglycolysis-associated oxidative injury from excessive production of reactive oxygen species (ROS). Clinically, to address hyperglycemia in stroke, insulin has been implemented to normalize serum gluco...



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