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Funded Project Details - FY2021

Project Number:

Title: A Minimally Invasive Platform to Target, Image, and Treat Head and Neck Cancer
Principal Investigator:

Hadiyah-Nicole Green

Location: Birmingham, AL
Congressional District Code: 7
Research Service: Rehabilitation R&D
Project Period: May 2016 - October 2021
FY 2021 Funding Amount: $230,903
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


 DESCRIPTION (provided by applicant): This proposal combines fluorescent imaging, active targeting, and subsequent photothermal treatment of malignant cells as an approach for treating head and neck cancers. The use of a near-infrared (NIR) laser enables us to take advantage of both the plasmon resonance absorption peak of gold nanorods (AuNRs), ~785 nm, as well as the absorption peak of the fluorescent dye, ~774 nm. We propose to label anti-EGFR antibodies, which target the over-expresse...

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