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Funded Project Details - FY2021

Project Number:

Title: Mechanisms of Breaking Indolence in Squamous Cell Carcinoma
Principal Investigator:

Xiao-Jing Wang

Location: Denver, CO
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: October 2016 - March 2021
FY 2021 Funding Amount: $80,870
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


 DESCRIPTION (provided by applicant): Human squamous cell carcinomas (SCCs) arising from the skin and oral cavity can present in an indolent form, similar to hibernation, with no obvious tumor expansion or local/systemic invasion. SCC indolence, which restricts net tumor expansion and invasion at the primary site, is severely understudied. Very little is known about why indolent SCCs persist and when they evolve into an aggressive form. Without molecular and cellular markers of SCC in...

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