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Funded Project Details - FY2021




Project Number:

I01BX001729-05A1
Title: Regulation of the Nox1 NADPH Oxidase in Vascular Smooth Muscle Cells
Principal Investigator:

Francis J. Miller

Location: Durham, NC
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: September 2016 - March 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$680,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

 DESCRIPTION (provided by applicant): Chronic inflammatory diseases, such as, rheumatoid arthritis (RA), are associated with premature development of cardiovascular disease (CVD). Mortality rates among US Veterans with RA are more than twice that of age-matched men in the general population, a risk that appears to be higher than that observed in other RA cohorts. Despite strong evidence that chronic inflammation accelerates CVD, currently available treatments are not sufficient to pre...



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