Funded Project Details - FY2021
|Title:|| Mechanisms of Virus-induced Injury in the Brain and Spinal Cord|
Kenneth L. Tyler
|Congressional District Code:
||Biomedical Laboratory R&D
|| January 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
DESCRIPTION (provided by applicant): Treatments for virus-induced diseases of the central nervous system (CNS) are sub-optimal or non- existent. Virus infection of the CNS results in a robust host neuroinflammatory response, defined by the activation of resident CNS immune cells (microglia and astrocytes) and the up-regulation of pro-inflammatory genes. The role of these responses in virus-induced CNS disease remains unclear. Neuroinflammatory responses likely play a protective role...
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