Funded Project Details - FY2021
|Title:|| Regulation of Functional Activity of Osteoclasts|
K. H. William Lau
||Loma Linda, CA
|Congressional District Code:
||Biomedical Laboratory R&D
|| July 2016 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
DESCRIPTION (provided by applicant): Past work of this group has demonstrated that an osteoclastic protein-tyrosine phosphatase (PTP-oc) is a positive activator of the osteoclast activity. Recent preliminary studies have disclosed four exciting discoveries relevant to the mechanism of how PTP-oc expression in osteoclasts is regulated: First, PTP-oc expression is controlled primarily by post-transcriptional mechanisms. Second, the post-transcriptional regulation of PTP-oc expression in o...
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