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Project Number: | I01BX000733-05 |
| Title: | Hexokinase 2 and cancer therapy |
| Principal Investigator: | Nissim Hay |
| Location: | Chicago, IL |
| Congressional District Code: | 7 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2016 - June 2021 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$963,627 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by PI): Cancer cells are metabolically different from normal matching cells, and this is manifested by the high rate of glucose metabolism in cancer cells. Because high rate of aerobic glycolysis distinguishes cancer cells from normal cells it is exploited for the selective imaging of cancer cells in vivo through the utilization of the glucose analog fluoro-2-deoxyglucose (FDG) in positron emission tomography (PET). PET is used following injection of [18F]-FDG,... |