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Project Number: | I01CX001481-01 |
| Title: | Shedding light on glaucoma: optogenetics regulation of ciliary phosphoinositides |
| Principal Investigator: | Yang Sun |
| Location: | Palo Alto, CA |
| Congressional District Code: | 7 |
| Research Service: | Clinical Science R&D |
| Project Period: | October 2016 - September 2022 |
| FY 2021 Funding Amount: | $54,999 |
| Total Award Amount (all years): |
$693,596 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant): Glaucoma is a leading cause of irreversible blindness in the world, and it affects more than 285,000 U.S. veterans. Elevated intraocular pressure (IOP) is associated with both development and progression of primary open angle glaucoma, and IOP is the only modifiable risk factor for the disease. However, the mechanisms causing elevated IOP remain poorly understood. Trabecular meshwork cells are critical to maintaining a normal aqueous fluid flow an... |