Office of Research & Development |
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Project Number: | IK2RX002013-01A2 |
Title: | Designing Neural Tissue Constructs that Mimic Brain-Specific Architecture |
Principal Investigator: | Han-Chiao I Chen |
Location: | Philadelphia, PA |
Congressional District Code: | 2 |
Research Service: | Rehabilitation R&D |
Project Period: | June 2016 - December 2021 |
FY 2021 Funding Amount: | $373,001 |
Total Award Amount (all years): |
$1,950,621 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Designing neuronal tissue constructs that mimic brain-specific architecture Objective(s): This proposal develops an in vivo approach for repairing damaged cerebral cortex circuits with engineered neural tissue. Specifically, the proposed studies seek to generate transplantable constructs with attributes of grey and white matter structure to optimize their match to normal brain architecture. Upon transplantation, these constructs will be evaluated for their survival and integration into host brai... |