Project Number:

Han-Chiao I Chen

Designing neuronal tissue constructs that mimic brain-specific architecture Objective(s): This proposal develops an in vivo approach for repairing damaged cerebral cortex circuits with engineered neural tissue. Specifically, the proposed studies seek to generate transplantable constructs with attributes of grey and white matter structure to optimize their match to normal brain architecture. Upon transplantation, these constructs will be evaluated for their survival and integration into host brai...