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Funded Project Details - FY2021

Project Number:

Title: IRF8 and lymphomagenesis
Principal Investigator:

Ricardo C Aguiar

Location: San Antonio, TX
Congressional District Code: 21
Research Service: Biomedical Laboratory R&D
Project Period: April 2017 - March 2021
FY 2021 Funding Amount: $187,862
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The advent of massive parallel sequencing highlighted the genetic complexity of cancer, and unveiled the putative contribution of several unsuspected genes to the process of malignant transformation. These advances also indicated a need for the systematic examination of newly-found mutant genes as to determine whether they truly contribute to cancer pathogenesis, or simply represent innocuous variants irrelevant to the observed phenotype. Diffuse large B cell lymphoma (DLBCL), the most common ly...

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