Funded Project Details - FY2021
|Title:|| Regulation of Calcium Signaling in Retinal Ganglion Cells after Nerve Injury|
||West Los Angeles, CA
|Congressional District Code:
||Biomedical Laboratory R&D
|| January 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Abstract Severe reductions of vision and blindness due to ocular disease and trauma are major clinical problems that have serious consequences on the Veteran's quality of life. Optic neuropathies from injury to the retina and optic nerve are characterized by a loss of ganglion cells and their axons. Ganglion cell death is initiated by excessive intracellular Ca2+ levels followed by a cascade of deleterious cellular processes that result in apoptosis. Consistent with this observation is the enhan...
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