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Funded Project Details - FY2021




Project Number:

I01BX003188-01A1
Title: Functionally-selective parathyroid hormone analogs as therapeutics in metabolic bone disease
Principal Investigator:

Louis M. Luttrell

Location: Charleston, SC
Congressional District Code: 6
Research Service: Biomedical Laboratory R&D
Project Period: October 2016 - March 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$673,174
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Osteoporosis is an aging related condition characterized by progressive loss of bone mass and increasing bone fragility that affects many Veteran men and women. Given the tremendous morbidity and excess mortality associated with osteoporosis-related fracture, it is vital to the VA healthcare mission to explore novel strategies to reduce fracture risk. The only current FDA-approved anabolic therapy for severe osteoporosis is teriparatide [hPTH(1-34)], a conventional agonist of the type 1 parathyr...



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