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Funded Project Details - FY2021




Project Number:

I01BX001963-05
Title: AKIP1 regulation of PKA and NF-KB in the heart
Principal Investigator:

Hemal H Patel

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: April 2017 - September 2021
FY 2021 Funding Amount: $82,500
Total Award Amount
(all years):
$1,068,857
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Cardiovascular disease is the leading cause of morbidity and mortality in the United States with >50% of mortality attributed to coronary artery disease. Though ischemic preconditioning, an endogenous protective mechanism used to salvage ischemic myocardium, was described nearly 25 years ago, there has been little to no clinical translation. Protective mechanisms in the heart utilize a number of pathways; however, unifying control points that might integrate this protective response need further...



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