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Project Number: | I01BX001963-05 |
| Title: | AKIP1 regulation of PKA and NF-KB in the heart |
| Principal Investigator: | Hemal H Patel |
| Location: | San Diego, CA |
| Congressional District Code: | 52 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2017 - September 2021 |
| FY 2021 Funding Amount: | $82,500 |
| Total Award Amount (all years): |
$1,068,857 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Cardiovascular disease is the leading cause of morbidity and mortality in the United States with >50% of mortality attributed to coronary artery disease. Though ischemic preconditioning, an endogenous protective mechanism used to salvage ischemic myocardium, was described nearly 25 years ago, there has been little to no clinical translation. Protective mechanisms in the heart utilize a number of pathways; however, unifying control points that might integrate this protective response need further... |