Funded Project Details - FY2021
|Title:|| A Novel Mechanism Regulating Virulence in Acinetobacter baumannii|
Philip N. Rather
|Congressional District Code:
||Biomedical Laboratory R&D
|| April 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
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Acinetobacter baumannii is a nosocomial pathogen responsible for an increasing number of infections in VA, civilian and military hospitals. This proposal will address a novel mechanism that regulates virulence in A. baumannii. This mechanism involves a molecular switch that interconverts A. baumannii between virulent and avirulent states. Cells in the virulent state grow as opaque colonies when viewed by indirect oblique lighting. In contrast, the avirulent form produces translucent colonies tha...
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