Funded Project Details - FY2021
|Title:|| Pathways regulating adult pancreatic beta cell replication|
|Congressional District Code:
||Biomedical Laboratory R&D
|| October 2016 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
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Project Summary/Abstract Type 2 diabetes (T2D) disproportionately affects the Veteran population: while 9% percent of the total US population has T2D, 25% of the Veteran population suffers from this disease. Adult β cell mass normally increases via replication in response to insulin resistance, but failure of β cell proliferation plus increased β cell death lead to T2D. T2D incidence increases with age, in part due to a decreased ability of β cells to respond to proliferative cues as they get ol...
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