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Funded Project Details - FY2021




Project Number:

I01BX001426-05A1
Title: Modulation of junctional signaling by BVES in colorectal carcinoma
Principal Investigator:

Christopher S Williams

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: January 2017 - December 2020
FY 2021 Funding Amount: $41,250
Total Award Amount
(all years):
$683,750
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Colorectal cancer (CRC) has a US incidence rate of almost 150,000 cases encompassing over 10% of new cancer diagnoses. In 2006 Within the Veterans Administration Healthcare System there were 4500 new cases and of those 650 were at advanced stage with very limited treatment options. Understanding the basic biology of underlying malignant transformation is critical in identifying new therapeutic targets and implementable strategies. Epithelial junctional pathology is common in malignancy. BVES is...



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