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Funded Project Details - FY2021

Project Number:

Title: Treating PTSD and depression: Mechanisms of pharmacotherapy and psychotherapy in rats
Principal Investigator:

David Morilak

Location: San Antonio, TX
Congressional District Code: 21
Research Service: Biomedical Laboratory R&D
Project Period: January 2017 - December 2020
FY 2021 Funding Amount: $98,252
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


PTSD and depression are serious psychiatric disorders afflicting the veteran population, and are frequently comorbid. Current pharmaco- and psychotherapies are inadequate, and more effective treatments are needed. Progress has been hampered by a lack of understanding of the neurobiological mechanisms underlying the pathology and effective treatment of these disorders. We have used chronic unpredictable stress (CUS) to produce behavioral changes in rats that model several shared dimensions of PTS...

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