Funded Project Details - FY2021
|Title:|| Understanding Susceptibility to Parkinson's Disease due to GBA1 Mutations|
Marie Y Davis
|Congressional District Code:
||Biomedical Laboratory R&D
|| January 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
PROJECT SUMMARY Parkinson’s disease (PD) is the second most common neurodegenerative disease, and ~60,000 veterans currently receive care for PD from the VA Health Care System annually. PD is characterized by progressive motor decline and cognitive impairment. Despite significant medical burden, our understanding of the pathogenesis of PD and therapies remain limited. Mutations in the gene glucosidase, beta acid 1 (GBA1) are the strongest genetic risk factor for developing idiopathic PD, incre...
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