Office of Research & Development |
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Project Number: | I01CX001553-04A1 |
Title: | Cross-talk between lung natural killer cells and dendritic cells in COPD |
Principal Investigator: | Christine M Basmajian |
Location: | Ann Arbor, MI |
Congressional District Code: | 12 |
Research Service: | Clinical Science R&D |
Project Period: | January 2017 - December 2021 |
FY 2021 Funding Amount: | $190,987 |
Total Award Amount (all years): |
$1,459,648 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Chronic obstructive pulmonary disease (COPD) is the 3rd leading cause of death in the United States, yet there are no current therapeutic treatments to halt disease progression. Airway inflammation and parenchymal destruction are central to the pathogenesis of COPD. Numerous inflammatory cell types have been implicated in COPD but an understanding of how these cell types contribute to lung destruction is lacking. Natural killer cells (NKs), an important component of the innate immune system, are... |