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Funded Project Details - FY2021




Project Number:

I01CX001553-04A1
Title: Cross-talk between lung natural killer cells and dendritic cells in COPD
Principal Investigator:

Christine M Basmajian

Location: Ann Arbor, MI
Congressional District Code: 12
Research Service: Clinical Science R&D
Project Period: January 2017 - December 2021
FY 2021 Funding Amount: $190,987
Total Award Amount
(all years):
$1,459,648
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Chronic obstructive pulmonary disease (COPD) is the 3rd leading cause of death in the United States, yet there are no current therapeutic treatments to halt disease progression. Airway inflammation and parenchymal destruction are central to the pathogenesis of COPD. Numerous inflammatory cell types have been implicated in COPD but an understanding of how these cell types contribute to lung destruction is lacking. Natural killer cells (NKs), an important component of the innate immune system, are...



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