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Funded Project Details - FY2021




Project Number:

I01CX001430-01A2
Title: Sex hormones and HCV-related liver disease progression
Principal Investigator:

Donna L. White

Location: Houston, TX
Congressional District Code: 9
Research Service: Clinical Science R&D
Project Period: July 2017 - December 2021
FY 2021 Funding Amount: $266,026
Total Award Amount
(all years):
$1,136,484
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Over 260,000 male veterans accessing VA healthcare between 2000 and 2014 had a laboratory confirmed diagnosis of hepatitis C virus (HCV) infection. Chronic HCV infection (HCV+) is the leading cause of liver disease progression to cirrhosis, liver transplant and liver cancer. HCV+ males have much higher rates of liver disease progression than HCV+ females. One factor that may contribute to this difference is large and gender- defining biological differences in the levels of circulating sex hormon...



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