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Funded Project Details - FY2021

Project Number:

Title: Surgical Studies on the Role of MicroRNAs in Esophageal Cancer
Principal Investigator:

James Donahue

Location: Birmingham, AL
Congressional District Code: 7
Research Service: Clinical Science R&D
Project Period: January 2017 - December 2021
FY 2021 Funding Amount: $110,250
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Background: Despite significant reductions in the morbidity and mortality associated with esophagectomy, survival for patients with esophageal cancer remains dismal. In most patients, adjunctive therapies including chemotherapy and radiation are beneficial. In fact, patients who achieve a complete pathologic response (pCR) after treatment with chemotherapy and radiation followed by esophagectomy often experience greatly improved survival. Unfortunately, the percentage of patients who currently a...

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