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Project Number: | I01CX001464-01A1 |
| Title: | Impact of HIV-1 and Aging on Mucosal Vaccine Responses |
| Principal Investigator: | Edward N. Janoff |
| Location: | Denver, CO |
| Congressional District Code: | 1 |
| Research Service: | Clinical Science R&D |
| Project Period: | January 2017 - December 2020 |
| FY 2021 Funding Amount: | $41,250 |
| Total Award Amount (all years): |
$683,750 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: 7. Project Summary/Abstract Both advancing age and HIV-1 infection are associated with an increased frequency of infection, such as those due to Streptococcus pneumoniae, and a higher rate of complications and death with these infections. Vaccines are available to prevent a number of infections common in older adults, such as pneumococcal pneumonia and blood stream infection. However, many older adults, particularly those with underlying disease, and persons living with HIV-1 infection show a de... |