Funded Project Details - FY2021
|Title:|| Modulating microglial phenotype to prevent SCI-induced central neuropathic pain|
|Congressional District Code:
|| June 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
A significant percentage (40-50%) of individuals with spinal cord injury (SCI) exhibit central neuropathic pain (CNP), a condition of persistent discomfort involving often unbearable burning, pricking, shooting and/or evoked types of pain in response to light touch. CNP appears more frequently in females, who also exhibit a greater sensitivity to pain than males. CNP develops in response to a dysregulation of somatosensory signaling and is largely refractory to conventional therapeutic intervent...
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