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Funded Project Details - FY2021




Project Number:

I01RX001311-01A2
Title: Overcoming Exercise Intolerance in Veterans with Heart Failure: The Role of NO.
Principal Investigator:

David Walter Wray

Location: Salt Lake City, UT
Congressional District Code: 2
Research Service: Rehabilitation R&D
Project Period: July 2017 - June 2021
FY 2021 Funding Amount: $206,048
Total Award Amount
(all years):
$1,098,924
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Heart failure with reduced ejection fraction (HFrEF), a clinical syndrome that develops as a consequence of heart disease from multiple etiologies, now affects almost six million Americans, presenting an imminent need for further research addressing the pathophysiology of this pervasive disease. One of the most damaging consequences of the disease is an elevation in sympathetic nervous system (SNS) activity, which manifests peripherally as chronic vasoconstriction. In HFrEF patients, peripheral...



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