Funded Project Details - FY2021
|Title:|| Mitochondrial CAMKII in smooth muscle as key regulator of hypertension and vascular remodeling|
||Iowa City, IA
|Congressional District Code:
||Biomedical Laboratory R&D
|| July 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Despite multiple initiatives in the VA healthcare system, at least 30% of the estimated three million Veterans with hypertension do not reach the current target blood pressure (BP). Hypertension induces pathological remodeling of the vascular wall, leading to further increases in BP and end organ dysfunction. These effects are linked to 5,000 annual deaths among Veterans. Emerging data suggest that mitochondrial ROS production is a common denominator in hypertension, but mechanistic concepts of...
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