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Funded Project Details - FY2021




Project Number:

I01BX003876-01
Title: Therapeutic potential of Palmatine in pancreatic cancer
Principal Investigator:

Addanki P Kumar

Location: San Antonio, TX
Congressional District Code: 21
Research Service: Biomedical Laboratory R&D
Project Period: July 2017 - June 2021
FY 2021 Funding Amount: $236,631
Total Award Amount
(all years):
$1,184,866
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Current projections predict pancreatic ductal adenocarcinoma (PDAC) will become the second leading cause of cancer-related deaths surpassing breast, prostate and colorectal cancers by 2030. Lack of treatment strategies that can reduce the near equal incidence and mortality rate is a barrier for this disease. A key feature of PDAC is desmoplasia, which is characterized by increased fibrosis and inflammation. Desmoplasia plays a critical role not only in pancreas pathogenesis but also in tumor mai...



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