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Project Number: | I01BX003876-01 |
| Title: | Therapeutic potential of Palmatine in pancreatic cancer |
| Principal Investigator: | Addanki P Kumar |
| Location: | San Antonio, TX |
| Congressional District Code: | 21 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2017 - June 2021 |
| FY 2021 Funding Amount: | $236,631 |
| Total Award Amount (all years): |
$1,184,866 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Current projections predict pancreatic ductal adenocarcinoma (PDAC) will become the second leading cause of cancer-related deaths surpassing breast, prostate and colorectal cancers by 2030. Lack of treatment strategies that can reduce the near equal incidence and mortality rate is a barrier for this disease. A key feature of PDAC is desmoplasia, which is characterized by increased fibrosis and inflammation. Desmoplasia plays a critical role not only in pancreas pathogenesis but also in tumor mai... |