Targeting Platelet Endocytosis and Exocytosis to Control Thrombosis
Congressional District Code:
Biomedical Laboratory R&D
October 2017 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
World-wide, spurious thrombosis accounts for 1 of 4 non-communicable disease deaths. Cardiovascular disease is a leading killer of aging US veterans and is the major cause of death in older female veterans. Understanding how to modulate thrombosis will significantly aide the VA's mission to improve veterans' health. Normally platelets respond to vascular damage and secrete granule cargo that are essential for recruiting more platelets and for generating a thrombus. This releasate promotes normal...