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Funded Project Details - FY2021

Project Number:

Title: Paracrine Mechanisms of Prostate Cancer Metastatic Progression
Principal Investigator:

Neil A Bhowmick

Location: Sepulveda, CA
Congressional District Code: 33
Research Service: Biomedical Laboratory R&D
Project Period: July 2017 - June 2021
FY 2021 Funding Amount: $222,898
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Prostate cancer is lethal when it metastasizes to the liver. We have identified for the first time that a steatotic hepatitis (fatty liver) is significantly more receptive to prostate cancer cells than a normal healthy liver. The Veteran population is predisposed to PCa liver metastasis as they have the multiple risk factors for fatty liver. In the course of this proposal our objective is to determine the mechanism of this interesting metastatic phenomena. We have demonstrated that the fatty liv...

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