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Funded Project Details - FY2021

Project Number:

Title: Re-engineering the tumor draining lymph node to achieve memory T cell-based adoptive immunotherapy
Principal Investigator:

Clifford S Cho

Location: Ann Arbor, MI
Congressional District Code: 12
Research Service: Biomedical Laboratory R&D
Project Period: October 2017 - June 2022
FY 2021 Funding Amount: $96,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Recent advances in immunotherapy have completely transformed the treatment and prognosis of veterans with advanced melanoma. Checkpoint inhibition immunotherapy using anti-CTLA-4 and anti-PD-1 antibodies has introduced the possibility of cure for a disease that was once practically untreatable. Sadly, the majority of veterans with metastatic melanoma will still succumb despite treatment, and incremental improvements in efficacy have brought increasing risks of autoimmune complications. For veter...

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