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Project Number: | I01BX003443-01A2 |
| Title: | Regulation of intestinal NaCl absorption |
| Principal Investigator: | Uma Sundaram |
| Location: | Huntington, WV |
| Congressional District Code: | 3 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2017 - June 2022 |
| FY 2021 Funding Amount: | $117,600 |
| Total Award Amount (all years): |
$691,250 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Diarrheal diseases afflict U.S. Veterans both at home and abroad. While the causes may be more acute overseas and more chronic in U.S., diarrhea in these conditions is a result of altered electrolyte (e.g. Na, Cl) and fluid transport in the intestine. For example, alterations in epithelial electrolyte transporters (e.g. Na:H and Cl:HCO3 exchange) is caused by immune inflammatory mediators known to be elevated in the mucosa of the chronically inflamed intestine (e.g. Inflammatory bowel disease, I... |