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Funded Project Details - FY2021




Project Number:

I01BX003742-01A1
Title: GRM1-induced HIF-1? and reprogramming of glutamine metabolisms in melanoma
Principal Investigator:

Suzie Chen

Location: East Orange, NJ
Congressional District Code: 10
Research Service: Biomedical Laboratory R&D
Project Period: October 2017 - March 2021
FY 2021 Funding Amount: $46,383
Total Award Amount
(all years):
$823,323
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

A new emerging hallmark for many malignancies is altered metabolic direction to support rapid cell proliferation. Considerable progress has been made in elucidating how modified cell signaling contributes to deregulated cell growth in cancer, much less is known regarding metabolic rewiring to provide for the demand in building blocks to support the ever-increasing cell numbers. Within the last few years metabolite profiling between normal and cancer cells has provided new insights to uncover the...



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